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Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine‐Cysteine Interaction

Tau protein is a natively unfolded protein whose primary role is to participate in axonal transport closely associated with microtubules. Neurodegenerative disorders including Alzheimer's disease and Tauopathies involved tau protein that is found hyperphosphorylated in vivo; then, tau is detach...

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Detalles Bibliográficos
Autores principales: Areche, Carlos, Zapata, Francisca, González, Mathias, Díaz, Esteban, Montecinos, Rubén, Hernández, Marcos, Melo, Francisco, Cornejo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496470/
https://www.ncbi.nlm.nih.gov/pubmed/31065505
http://dx.doi.org/10.1002/open.201800222