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Anthraquinone Derivative Reduces Tau Oligomer Progression by Inhibiting Cysteine‐Cysteine Interaction
Tau protein is a natively unfolded protein whose primary role is to participate in axonal transport closely associated with microtubules. Neurodegenerative disorders including Alzheimer's disease and Tauopathies involved tau protein that is found hyperphosphorylated in vivo; then, tau is detach...
Autores principales: | Areche, Carlos, Zapata, Francisca, González, Mathias, Díaz, Esteban, Montecinos, Rubén, Hernández, Marcos, Melo, Francisco, Cornejo, Alberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6496470/ https://www.ncbi.nlm.nih.gov/pubmed/31065505 http://dx.doi.org/10.1002/open.201800222 |
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