Molecular understanding of calcium permeation through the open Orai channel

The Orai channel is characterized by voltage independence, low conductance, and high Ca(2+) selectivity and plays an important role in Ca(2+) influx through the plasma membrane (PM). How the channel is activated and promotes Ca(2+) permeation is not well understood. Here, we report the crystal struc...

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Detalles Bibliográficos
Autores principales: Liu, Xiaofen, Wu, Guangyan, Yu, Yi, Chen, Xiaozhe, Ji, Renci, Lu, Jing, Li, Xin, Zhang, Xing, Yang, Xue, Shen, Yuequan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497303/
https://www.ncbi.nlm.nih.gov/pubmed/31009446
http://dx.doi.org/10.1371/journal.pbio.3000096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497303/
https://www.ncbi.nlm.nih.gov/pubmed/31009446
http://dx.doi.org/10.1371/journal.pbio.3000096

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