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Molecular understanding of calcium permeation through the open Orai channel
The Orai channel is characterized by voltage independence, low conductance, and high Ca(2+) selectivity and plays an important role in Ca(2+) influx through the plasma membrane (PM). How the channel is activated and promotes Ca(2+) permeation is not well understood. Here, we report the crystal struc...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497303/ https://www.ncbi.nlm.nih.gov/pubmed/31009446 http://dx.doi.org/10.1371/journal.pbio.3000096 |