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Expression estimation and eQTL mapping for HLA genes with a personalized pipeline
The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulatio...
Autores principales: | Aguiar, Vitor R. C., César, Jônatas, Delaneau, Olivier, Dermitzakis, Emmanouil T., Meyer, Diogo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497317/ https://www.ncbi.nlm.nih.gov/pubmed/31009447 http://dx.doi.org/10.1371/journal.pgen.1008091 |
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