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Tumor-infiltrating mucosal-associated invariant T (MAIT) cells retain expression of cytotoxic effector molecules
Mucosal-associated invariant T (MAIT) cells all express a semi-invariable T cell receptor recognizing microbial metabolites presented on the MHC class I-like molecule MR1. Upon activation, they rapidly secrete cytokines and increase their cytotoxic potential. We showed recently that MAIT cells with...
Autores principales: | Sundström, Patrik, Szeponik, Louis, Ahlmanner, Filip, Sundquist, Malin, Wong, Justin S.B., Lindskog, Elinor Bexe, Gustafsson, Bengt, Quiding-Järbrink, Marianne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497460/ https://www.ncbi.nlm.nih.gov/pubmed/31073372 http://dx.doi.org/10.18632/oncotarget.26866 |
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