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12(S)‐hydroxyeicosatetraenoic acid impairs vascular endothelial permeability by altering adherens junction phosphorylation levels and affecting the binding and dissociation of its components in high glucose‐induced vascular injury

AIMS/INTRODUCTION: Diabetes is an important risk factor for atherosclerotic disease. The initiating factor of atherosclerosis is local endothelial cell injury. The arachidonic acid metabolite, 12(S)‐hydroxyeicosatetraenoic acid (12[S]‐HETE), might be involved in this process. In recent years, some s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Gao, Lu, Xiao, Lili, Yang, Lulu, Li, Wenshu, Liu, Gangqiong, Chen, Linlin, Zhang, Jinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497583/
https://www.ncbi.nlm.nih.gov/pubmed/30251333
http://dx.doi.org/10.1111/jdi.12941