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Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function

The diagnosis and prognosis of chronic kidney disease (CKD) currently relies on very few circulating small molecules, which can vary by factors unrelated to kidney function. In end-stage renal disease (ESRD), these same small molecules are used to determine dialysis dose and dialytic clearance. Ther...

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Detalles Bibliográficos
Autores principales: Velenosi, Thomas J., Thomson, Benjamin K. A., Tonial, Nicholas C., RaoPeters, Adrien A. E., Mio, Megan A., Lajoie, Gilles A., Garg, Amit X., House, Andrew A., Urquhart, Bradley L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497643/
https://www.ncbi.nlm.nih.gov/pubmed/31048706
http://dx.doi.org/10.1038/s41598-019-42992-3