Impaired smooth muscle cell contractility as a novel concept of abdominal aortic aneurysm pathophysiology

Ruptured abdominal aortic aneurysms (AAA) are associated with overall mortality rates up to 90%. Despite extensive research, mechanisms leading to AAA formation and advancement are still poorly understood. Smooth muscle cells (SMC) are predominant in the aortic medial layer and maintain the wall str...

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Detalles Bibliográficos
Autores principales: Bogunovic, Natalija, Meekel, Jorn P., Micha, Dimitra, Blankensteijn, Jan D., Hordijk, Peter L., Yeung, Kak K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497672/
https://www.ncbi.nlm.nih.gov/pubmed/31048749
http://dx.doi.org/10.1038/s41598-019-43322-3

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