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Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation
Mutations in the nucleophosmin 1 (NPM1) gene are considered founder mutations in the pathogenesis of acute myeloid leukemia (AML). To characterize the genetic composition of NPM1 mutated (NPM1(mut)) AML, we assess mutation status of five recurrently mutated oncogenes in 129 paired NPM1(mut) samples...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497712/ https://www.ncbi.nlm.nih.gov/pubmed/31048683 http://dx.doi.org/10.1038/s41467-019-09745-2 |