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IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth

While IL-12 plays a key role in differentiation of protective CD4(+) Th1 response, little is known about mechanisms whereby IL-12 differentiates other T-cell populations. Published studies suggest that predominant Vγ2Vδ2 T cells in humans/nonhuman primates (NHP) are a fast-acting T-cell subset, with...

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Detalles Bibliográficos
Autores principales:	Yang, Rui, Yao, Lan, Shen, Ling, Sha, Wei, Modlin, Robert L., Shen, Hongbo, Chen, Zheng W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497761/ https://www.ncbi.nlm.nih.gov/pubmed/31080452 http://dx.doi.org/10.3389/fimmu.2019.00913

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