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Restrained Dendritic Growth of Adult-Born Granule Cells Innervated by Transplanted Fetal GABAergic Interneurons in Mice with Temporal Lobe Epilepsy
The dentate gyrus (DG) is a region of the adult rodent brain that undergoes continuous neurogenesis. Seizures and loss or dysfunction of GABAergic synapses onto adult-born dentate granule cells (GCs) alter their dendritic growth and migration, resulting in dysmorphic and hyperexcitable GCs. Addition...
Autores principales: | Gupta, Jyoti, Bromwich, Mark, Radell, Jake, Arshad, Muhammad N., Gonzalez, Selena, Luikart, Bryan W., Aaron, Gloster B., Naegele, Janice R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497906/ https://www.ncbi.nlm.nih.gov/pubmed/31043461 http://dx.doi.org/10.1523/ENEURO.0110-18.2019 |
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