WFDC2 contributes to epithelial–mesenchymal transition (EMT) by activating AKT signaling pathway and regulating MMP-2 expression

Objective: To understand the role of WFDC2 in metastasis of ovarian cancer. Methods: By knockdown or overexpression of WFDC2, we demonstrated the role of WFDC2 in epithelial–mesenchymal transition (EMT). Results: We demonstrated that stable knockdown of WFDC2 suppressed EMT along with the upregulati...

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Detalles Bibliográficos
Autores principales: Chen, Yao, Huang, Liping, Wang, Suihai, Li, Ji-Liang, Li, Ming, Wu, Yingsong, Liu, Tiancai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497977/
https://www.ncbi.nlm.nih.gov/pubmed/31118763
http://dx.doi.org/10.2147/CMAR.S192950

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