Cargando…

Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8(+) T-Cell Memory

Viral infection of cells is sensed by pathogen recognition receptors that trigger an antiviral innate immune response, and consequently viruses have evolved countermeasures. Vaccinia virus (VACV) evades the host immune response by expressing scores of immunomodulatory proteins. One family of VACV pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pallett, Mitchell A., Ren, Hongwei, Zhang, Rui-Yao, Scutts, Simon R., Gonzalez, Laura, Zhu, Zihan, Maluquer de Motes, Carlos, Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498060/
https://www.ncbi.nlm.nih.gov/pubmed/30814284
http://dx.doi.org/10.1128/JVI.00051-19