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Vaccinia Virus BBK E3 Ligase Adaptor A55 Targets Importin-Dependent NF-κB Activation and Inhibits CD8(+) T-Cell Memory
Viral infection of cells is sensed by pathogen recognition receptors that trigger an antiviral innate immune response, and consequently viruses have evolved countermeasures. Vaccinia virus (VACV) evades the host immune response by expressing scores of immunomodulatory proteins. One family of VACV pr...
Autores principales: | Pallett, Mitchell A., Ren, Hongwei, Zhang, Rui-Yao, Scutts, Simon R., Gonzalez, Laura, Zhu, Zihan, Maluquer de Motes, Carlos, Smith, Geoffrey L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498060/ https://www.ncbi.nlm.nih.gov/pubmed/30814284 http://dx.doi.org/10.1128/JVI.00051-19 |
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