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Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models
Studies in animal models are essential prerequisites for clinical trials of candidate HIV vaccines. Small animals, such as rabbits, are used to evaluate promising strategies prior to further immunogenicity and efficacy testing in nonhuman primates. Our goal was to determine how HIV-specific vaccine-...
Autores principales: | Pollara, Justin, Jones, Dorothy I., Huffman, Tori, Edwards, R. Whitney, Dennis, Maria, Li, Shuk Hang, Jha, Shalini, Goodman, Derrick, Kumar, Amit, LaBranche, Celia C., Montefiori, David C., Fouda, Genevieve G., Hope, Thomas J., Tomaras, Georgia D., Staats, Herman F., Ferrari, Guido, Permar, Sallie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498063/ https://www.ncbi.nlm.nih.gov/pubmed/30842326 http://dx.doi.org/10.1128/JVI.02119-18 |
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