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Multiplexed, Sequential Secretion Analysis of the Same Single Cells Reveals Distinct Effector Response Dynamics Dependent on the Initial Basal State

The effector response of immune cells dictated by an array of secreted proteins is a highly dynamic process, requiring sequential measurement of all relevant proteins from single cells. Herein, a microchip‐based, 10‐plexed, sequential secretion assay on the same single cells and at the scale of ≈500...

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Detalles Bibliográficos
Autores principales: Chen, Zhuo, Lu, Yao, Zhang, Kerou, Xiao, Yang, Lu, Jun, Fan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498135/
https://www.ncbi.nlm.nih.gov/pubmed/31065513
http://dx.doi.org/10.1002/advs.201801361