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CLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling

BACKGROUND: Claudin 8 (CLDN8), an integral membrane protein that constitutes tight junctions in cell membranes, was recently implicated in tumor progression. However, its roles in colorectal cancer (CRC) progression and metastasis remain unknown. METHODS: In this study, we examined the effect of CLD...

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Detalles Bibliográficos
Autores principales: Cheng, Bo, Rong, Aimei, Zhou, Quanbo, Li, Wenlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498432/
https://www.ncbi.nlm.nih.gov/pubmed/31118793
http://dx.doi.org/10.2147/CMAR.S189558