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CLDN8 promotes colorectal cancer cell proliferation, migration, and invasion by activating MAPK/ERK signaling
BACKGROUND: Claudin 8 (CLDN8), an integral membrane protein that constitutes tight junctions in cell membranes, was recently implicated in tumor progression. However, its roles in colorectal cancer (CRC) progression and metastasis remain unknown. METHODS: In this study, we examined the effect of CLD...
Autores principales: | Cheng, Bo, Rong, Aimei, Zhou, Quanbo, Li, Wenlu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498432/ https://www.ncbi.nlm.nih.gov/pubmed/31118793 http://dx.doi.org/10.2147/CMAR.S189558 |
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