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Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog

Diagnostic investigation and management of chronic diarrhoea in dogs can be cost‐prohibitive to many owners. The objectives of this study were to evaluate evidence‐based, individualised diagnostic and therapeutic protocols for management of dogs with chronic diarrhoea, where financial constraints di...

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Autores principales: Bryan, Christine E., Cade, Jeb C., Mackin, Andrew J., Sullivant, Alyssa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498526/
https://www.ncbi.nlm.nih.gov/pubmed/30746901
http://dx.doi.org/10.1002/vms3.154
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author Bryan, Christine E.
Cade, Jeb C.
Mackin, Andrew J.
Sullivant, Alyssa M.
author_facet Bryan, Christine E.
Cade, Jeb C.
Mackin, Andrew J.
Sullivant, Alyssa M.
author_sort Bryan, Christine E.
collection PubMed
description Diagnostic investigation and management of chronic diarrhoea in dogs can be cost‐prohibitive to many owners. The objectives of this study were to evaluate evidence‐based, individualised diagnostic and therapeutic protocols for management of dogs with chronic diarrhoea, where financial constraints dictate a budget‐limited approach and where more expensive approaches are deferred until simple affordable protocols are unsuccessful. Twenty‐two client‐owned dogs with chronic (minimum 2 weeks duration) untreated small, large or mixed small/large bowel diarrhoea were enrolled in a budget‐limited step‐wise management protocol (maximum expenditure $300 over 6 weeks), with diagnostic testing and therapeutic trials managed in an individualised and evidence‐based fashion. Success was defined as complete resolution of diarrhoea for a minimum of 1 month. Dogs that failed to respond to a budget‐limited protocol were then enrolled for complete, referral‐level management. Four dogs exited the project early (one death due to caval syndrome, three lost to follow‐up). Thirteen out of the remaining 18 dogs had complete resolution of diarrhoea utilising a budget‐limited approach (success rate 72.2%, confidence intervals 46.5–90.3%) and five dogs were moved on to a referral‐level investigation, with complete resolution of diarrhoea in four out of five. Seventeen out of the 18 dogs therefore responded to a protocol based on a budget‐limited approach followed by extensive investigation only if needed, for an overall success rate of 94.4% (CI 72.7–99.9%). Comprehensive investigation of chronic diarrhoea can be deferred while simple affordable diagnostics and therapeutic trials are conducted in stable canine patients and, often, an extensive management approach will be unnecessary.
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spelling pubmed-64985262019-05-07 Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog Bryan, Christine E. Cade, Jeb C. Mackin, Andrew J. Sullivant, Alyssa M. Vet Med Sci Original Articles Diagnostic investigation and management of chronic diarrhoea in dogs can be cost‐prohibitive to many owners. The objectives of this study were to evaluate evidence‐based, individualised diagnostic and therapeutic protocols for management of dogs with chronic diarrhoea, where financial constraints dictate a budget‐limited approach and where more expensive approaches are deferred until simple affordable protocols are unsuccessful. Twenty‐two client‐owned dogs with chronic (minimum 2 weeks duration) untreated small, large or mixed small/large bowel diarrhoea were enrolled in a budget‐limited step‐wise management protocol (maximum expenditure $300 over 6 weeks), with diagnostic testing and therapeutic trials managed in an individualised and evidence‐based fashion. Success was defined as complete resolution of diarrhoea for a minimum of 1 month. Dogs that failed to respond to a budget‐limited protocol were then enrolled for complete, referral‐level management. Four dogs exited the project early (one death due to caval syndrome, three lost to follow‐up). Thirteen out of the remaining 18 dogs had complete resolution of diarrhoea utilising a budget‐limited approach (success rate 72.2%, confidence intervals 46.5–90.3%) and five dogs were moved on to a referral‐level investigation, with complete resolution of diarrhoea in four out of five. Seventeen out of the 18 dogs therefore responded to a protocol based on a budget‐limited approach followed by extensive investigation only if needed, for an overall success rate of 94.4% (CI 72.7–99.9%). Comprehensive investigation of chronic diarrhoea can be deferred while simple affordable diagnostics and therapeutic trials are conducted in stable canine patients and, often, an extensive management approach will be unnecessary. John Wiley and Sons Inc. 2019-02-11 /pmc/articles/PMC6498526/ /pubmed/30746901 http://dx.doi.org/10.1002/vms3.154 Text en © 2019 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Bryan, Christine E.
Cade, Jeb C.
Mackin, Andrew J.
Sullivant, Alyssa M.
Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title_full Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title_fullStr Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title_full_unstemmed Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title_short Evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
title_sort evaluation of a structured individualised protocol as a potential cost‐effective diagnostic and therapeutic approach to chronic diarrhoea in the dog
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498526/
https://www.ncbi.nlm.nih.gov/pubmed/30746901
http://dx.doi.org/10.1002/vms3.154
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