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Scrutinizing the drug resistance mechanism of multi- and extensively-drug resistant Mycobacterium tuberculosis: mutations versus efflux pumps

BACKGROUND: In order to shorten the course of treatment and its effectiveness, it is essential to gain an in-depth insight into the drug resistance mechanisms of Mycobacterium tuberculosis (M. tuberculosis). METHODS: In this study, we evaluated the contribution of 26 drug efflux pumps plus target ge...

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Detalles Bibliográficos
Autores principales: Ghajavand, Hasan, Kargarpour Kamakoli, Mansour, Khanipour, Sharareh, Pourazar Dizaji, Shahin, Masoumi, Morteza, Rahimi Jamnani, Fatemeh, Fateh, Abolfazl, Yaseri, Mehdi, Siadat, Seyed Davar, Vaziri, Farzam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498538/
https://www.ncbi.nlm.nih.gov/pubmed/31073401
http://dx.doi.org/10.1186/s13756-019-0516-4