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A substitution in the pre-S1 promoter region is associated with the viral regulation of hepatitis B virus

BACKGROUND: Much evidence has demonstrated the influence of Hepatitis B virus (HBV) mutations on the clinical course of HBV infection. As large (L) protein plays a crucial role for viral entry, we hypothesized that mutations in the pre-S1 promoter region might affect the expression of L protein and...

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Detalles Bibliográficos
Autores principales:	Ogura, Suguru, Tameda, Masahiko, Sugimoto, Kazushi, Ikejiri, Makoto, Usui, Masanobu, Ito, Masaaki, Takei, Yoshiyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498540/ https://www.ncbi.nlm.nih.gov/pubmed/31046787 http://dx.doi.org/10.1186/s12985-019-1169-x

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