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A candidate DNA vaccine encoding a fusion protein of porcine complement C3d-P28 and ORF2 of porcine circovirus type 2 induces cross-protective immunity against PCV2b and PCV2d in pigs

BACKGROUND: Porcine circovirus type 2 (PCV2) is an economically important viral pathogen for swine industry worldwide. However, current PCV2 vaccines provide incomplete protection against the PCV2d, which has recently emerged as the predominant pathogenic form of PCV2. METHODS: To develop a novel DN...

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Detalles Bibliográficos
Autores principales: Hou, Zhumei, Wang, Honghua, Feng, Yanni, Li, Qingwang, Li, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498589/
https://www.ncbi.nlm.nih.gov/pubmed/31046793
http://dx.doi.org/10.1186/s12985-019-1156-2