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scruff: an R/Bioconductor package for preprocessing single-cell RNA-sequencing data
BACKGROUND: Single-cell RNA sequencing (scRNA-seq) enables the high-throughput quantification of transcriptional profiles in single cells. In contrast to bulk RNA-seq, additional preprocessing steps such as cell barcode identification or unique molecular identifier (UMI) deconvolution are necessary...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498700/ https://www.ncbi.nlm.nih.gov/pubmed/31046658 http://dx.doi.org/10.1186/s12859-019-2797-2 |