Cargando…
Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways
BACKGROUND: Promoters and enhancers are cis-regulatory DNA sequences that control specificity and quantity of transcription. Both are rich on clusters of cis-acting sites that interact with sequence-specific DNA-binding transcription factors (TFs). At the level of chromatin, these regions display in...
Autores principales: | Zhao, Yilin, Zheng, Deyou, Cvekl, Ales |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498704/ https://www.ncbi.nlm.nih.gov/pubmed/31053165 http://dx.doi.org/10.1186/s13072-019-0272-y |
Ejemplares similares
-
Dynamic changes in whole genome DNA methylation, chromatin and gene expression during mouse lens differentiation
por: Chang, William, et al.
Publicado: (2023) -
Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3
por: Martynova, Elena, et al.
Publicado: (2019) -
Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development
por: Sun, Jian, et al.
Publicado: (2015) -
Pax6 Interactions with Chromatin and Identification of Its Novel Direct Target Genes in Lens and Forebrain
por: Xie, Qing, et al.
Publicado: (2013) -
Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators
por: Sun, Jian, et al.
Publicado: (2015)