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Profiling of chromatin accessibility and identification of general cis-regulatory mechanisms that control two ocular lens differentiation pathways

BACKGROUND: Promoters and enhancers are cis-regulatory DNA sequences that control specificity and quantity of transcription. Both are rich on clusters of cis-acting sites that interact with sequence-specific DNA-binding transcription factors (TFs). At the level of chromatin, these regions display in...

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Detalles Bibliográficos
Autores principales: Zhao, Yilin, Zheng, Deyou, Cvekl, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498704/
https://www.ncbi.nlm.nih.gov/pubmed/31053165
http://dx.doi.org/10.1186/s13072-019-0272-y

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