Distinct Tumor Microenvironment at Tumor Edge as a Result of Astrocyte Activation Is Associated With Therapeutic Resistance for Brain Tumor

Tumor vasculatures and hypoxia are critical tumor micro-environmental factors associated with tumor response to the therapy and heterogeneous in both time- and location-dependent manner. Using a murine orthotopic anaplastic astrocytoma model, ALTS1C1, this study showed that brain tumor edge had a ve...

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Detalles Bibliográficos
Autores principales: Lin, Chiu-Min, Yu, Ching-Fang, Huang, Hsueh-Ya, Chen, Fang-Hsin, Hong, Ji-Hong, Chiang, Chi-Shiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498880/
https://www.ncbi.nlm.nih.gov/pubmed/31106146
http://dx.doi.org/10.3389/fonc.2019.00307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498880/
https://www.ncbi.nlm.nih.gov/pubmed/31106146
http://dx.doi.org/10.3389/fonc.2019.00307

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