Cargando…

Tangshen Formula Alleviates Hepatic Steatosis by Inducing Autophagy Through the AMPK/SIRT1 Pathway

Tangshen formula (TSF), a formula of Chinese herbal medicine, improves lipid metabolism in humans and animals with diabetic kidney disease. However, the effect and mechanism of TSF on nonalcoholic fatty liver disease (NAFLD) remain unclear. The activation of autophagy appears to be a potential mecha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yan, Zhao, Hailing, Li, Xin, Li, Nan, Wang, Qian, Liu, Yanzhen, Liang, Qionglin, Shao, Zixing, Zhang, Nannan, Zhao, Tingting, Peng, Liang, Li, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498888/ https://www.ncbi.nlm.nih.gov/pubmed/31105592 http://dx.doi.org/10.3389/fphys.2019.00494

Ejemplares similares

Tangshen Formula Attenuates Diabetic Nephropathy by Promoting ABCA1-Mediated Renal Cholesterol Efflux in db/db Mice
por: Liu, Peng, et al.
Publicado: (2018)

Tangshen formula attenuates diabetic renal injuries by upregulating autophagy via inhibition of PLZF expression
por: Zhao, Hailing, et al.
Publicado: (2017)

Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice
por: Kong, Qin, et al.
Publicado: (2016)

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in Rats
por: Zhao, TingTing, et al.
Publicado: (2016)

Tangshen Formula Attenuates Diabetic Kidney Injury by Imparting Anti-pyroptotic Effects via the TXNIP-NLRP3-GSDMD Axis
por: Li, Nan, et al.
Publicado: (2021)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes
por: Wang, Qian, et al.
Publicado: (2020)

Tangshen Formula Attenuates Colonic Structure Remodeling in Type 2 Diabetic Rats
por: Chen, Pengmin, et al.
Publicado: (2017)

Tangshen Formula Improves Diabetes-Associated Myocardial Fibrosis by Inhibiting TGF-β/Smads and Wnt/β-Catenin Pathways
por: Hu, Lin, et al.
Publicado: (2021)

SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy
por: Zhao, Wenyu, et al.
Publicado: (2018)

Role of AMPK in autophagy
por: Wang, Shengyuan, et al.
Publicado: (2022)

Effect of Tangshen formula on the remodeling of small intestine and colon in Zucker diabetic fatty rats
por: Yang, Xin, et al.
Publicado: (2023)

Liraglutide Alleviates Hepatic Steatosis and Liver Injury in T2MD Rats via a GLP-1R Dependent AMPK Pathway
por: Zhou, Rui, et al.
Publicado: (2021)

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array
por: Fan, Xue Mei, et al.
Publicado: (2018)

Empagliflozin Alleviates Hepatic Steatosis by Activating the AMPK-TET2-Autophagy Pathway in vivo and in vitro
por: Li, Ting, et al.
Publicado: (2021)

Mechanism of tangshen formula in treating diabetic nephropathy revealed by network pharmacology approach
por: Quan, Na, et al.
Publicado: (2021)

Tangshen Decoction Enhances Podocytes Autophagy to Relieve Diabetic Nephropathy through Modulation of p-AMPK/p-ULK1 Signaling
por: Yan, Ling, et al.
Publicado: (2022)

Effects of Tangshen Formula on urinary and plasma liver-type fatty acid binding protein levels in patients with type 2 diabetic kidney disease: post-hoc findings from a multi-center, randomized, double-blind, placebo-controlled trial investigating the efficacy and safety of Tangshen Formula in patients with type 2 diabetic kidney disease
por: Yang, Xin, et al.
Publicado: (2016)

Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway
por: Dong, Wenmin, et al.
Publicado: (2021)

MiR-22 Inhibition Alleviates Cardiac Dysfunction in Doxorubicin-Induced Cardiomyopathy by Targeting the sirt1/PGC-1α Pathway
por: Wang, Runze, et al.
Publicado: (2021)

AMPK-Regulated Autophagy Contributes to Ursolic Acid Supplementation-Alleviated Hepatic Steatosis and Liver Injury in Chronic Alcohol-Fed Mice
por: Ma, Yue, et al.
Publicado: (2022)

Attenuation of Diabetic Nephropathy in Otsuka Long-Evans Tokushima Fatty (OLETF) Rats with a Combination of Chinese Herbs (Tangshen Formula)
por: Zhang, Haojun, et al.
Publicado: (2011)

Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK
por: Huang, Qi, et al.
Publicado: (2017)

Phloretin ameliorates hepatic steatosis through regulation of lipogenesis and Sirt1/AMPK signaling in obese mice
por: Liou, Chian-Jiun, et al.
Publicado: (2020)

Icariin Inhibits AMPK-Dependent Autophagy and Adipogenesis in Adipocytes In vitro and in a Model of Graves' Orbitopathy In vivo
por: Li, Hong, et al.
Publicado: (2017)

Phosphodiesterase 4 inhibitor activates AMPK-SIRT6 pathway to prevent aging-related adipose deposition induced by metabolic disorder
por: Wang, Zhuoran, et al.
Publicado: (2018)

AMPK/mTOR Signaling in Autophagy Regulation During Cisplatin-Induced Acute Kidney Injury
por: Wang, Ying, et al.
Publicado: (2020)

Curcumin Alleviates D-Galactose-Induced Cardiomyocyte Senescence by Promoting Autophagy via the SIRT1/AMPK/mTOR Pathway
por: Yang, Lei, et al.
Publicado: (2022)

MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis
por: Hu, Liang-Kai, et al.
Publicado: (2021)

MicroRNA-506-3p targets SIRT1 and suppresses AMPK pathway activation to promote hepatic steatosis
por: Hu, Liang-Kai, et al.
Publicado: (2022)

Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway
por: Luo, Xiu-ying, et al.
Publicado: (2021)

Lactobacillus Strains Alleviated Hyperlipidemia and Liver Steatosis in Aging Rats via Activation of AMPK
por: Lew, Lee-Ching, et al.
Publicado: (2020)

Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes
por: He, Juan, et al.
Publicado: (2019)

Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1
por: Mao, Shuai, et al.
Publicado: (2018)

Resveratrol Improves the Energy Sensing and Glycolipid Metabolism of Blunt Snout Bream Megalobrama amblycephala Fed High-Carbohydrate Diets by Activating the AMPK–SIRT1–PGC-1α Network
por: Shi, Hua-Juan, et al.
Publicado: (2018)

CD38 Deficiency Alleviates D-Galactose-Induced Myocardial Cell Senescence Through NAD(+)/Sirt1 Signaling Pathway
por: Wang, Ling-Fang, et al.
Publicado: (2019)

Efficacy and Safety of Tangshen Formula on Patients with Type 2 Diabetic Kidney Disease: A Multicenter Double-Blinded Randomized Placebo-Controlled Trial
por: Li, Ping, et al.
Publicado: (2015)

Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway
por: Jing, Hui-Rong, et al.
Publicado: (2018)

Quercetin and AMPK: A Dynamic Duo in Alleviating MG-Induced Inflammation via the AMPK/SIRT1/NF-κB Pathway
por: Lu, Ziyin, et al.
Publicado: (2023)

Flavonones from Penthorum chinense Ameliorate Hepatic Steatosis by Activating the SIRT1/AMPK Pathway in HepG2 Cells
por: Guo, Wei-Wei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_agp9e1jcnk91n12uqkb937ee0d