Current Development of siRNA Bioconjugates: From Research to the Clinic

Small interfering RNAs (siRNAs) acting via RNA interference mechanisms are able to recognize a homologous mRNA sequence in the cell and induce its degradation. The main problems in the development of siRNA-based drugs for therapeutic use are the low efficiency of siRNA delivery to target cells and t...

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Detalles Bibliográficos
Autores principales: Chernikov, Ivan V., Vlassov, Valentin V., Chernolovskaya, Elena L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498891/
https://www.ncbi.nlm.nih.gov/pubmed/31105570
http://dx.doi.org/10.3389/fphar.2019.00444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498891/
https://www.ncbi.nlm.nih.gov/pubmed/31105570
http://dx.doi.org/10.3389/fphar.2019.00444

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