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Transgenic Exosomes for Thymus Regeneration

During senescence, Wnt4 expression is down-regulated (unlike their Frizzled receptors), while PPARgamma expression increases in the thymus. Together, these changes allow for thymic degeneration to occur, observed as adipose involution. However, when restored, Wnt4 can efficiently counteract PPARgamm...

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Detalles Bibliográficos
Autores principales:	Banfai, Krisztina, Garai, Kitti, Ernszt, David, Pongracz, Judit E., Kvell, Krisztian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499203/ https://www.ncbi.nlm.nih.gov/pubmed/31110503 http://dx.doi.org/10.3389/fimmu.2019.00862

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