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Accurate analysis of genuine CRISPR editing events with ampliCan

We present ampliCan, an analysis tool for genome editing that unites highly precise quantification and visualization of genuine genome editing events. ampliCan features nuclease-optimized alignments, filtering of experimental artifacts, event-specific normalization, and off-target read detection and...

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Detalles Bibliográficos
Autores principales:	Labun, Kornel, Guo, Xiaoge, Chavez, Alejandro, Church, George, Gagnon, James A., Valen, Eivind
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499316/ https://www.ncbi.nlm.nih.gov/pubmed/30850374 http://dx.doi.org/10.1101/gr.244293.118

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