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Laboratory validation of a clinical metagenomic sequencing assay for pathogen detection in cerebrospinal fluid

Metagenomic next-generation sequencing (mNGS) for pan-pathogen detection has been successfully tested in proof-of-concept case studies in patients with acute illness of unknown etiology but to date has been largely confined to research settings. Here, we developed and validated a clinical mNGS assay...

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Detalles Bibliográficos
Autores principales:	Miller, Steve, Naccache, Samia N., Samayoa, Erik, Messacar, Kevin, Arevalo, Shaun, Federman, Scot, Stryke, Doug, Pham, Elizabeth, Fung, Becky, Bolosky, William J., Ingebrigtsen, Danielle, Lorizio, Walter, Paff, Sandra M., Leake, John A., Pesano, Rick, DeBiasi, Roberta, Dominguez, Samuel, Chiu, Charles Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499319/ https://www.ncbi.nlm.nih.gov/pubmed/30992304 http://dx.doi.org/10.1101/gr.238170.118

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