Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

Developmental signal transduction pathways act diversely, with context-dependent roles across systems and disease types. Glioblastomas (GBMs), which are the poorest prognosis primary brain cancers, strongly resemble developmental systems, but these growth processes have not been exploited therapeuti...

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Detalles Bibliográficos
Autores principales: Rajakulendran, Nishani, Rowland, Katherine J., Selvadurai, Hayden J., Ahmadi, Moloud, Park, Nicole I., Naumenko, Sergey, Dolma, Sonam, Ward, Ryan J., So, Milly, Lee, Lilian, MacLeod, Graham, Pasiliao, Clarissa, Brandon, Caroline, Clarke, Ian D., Cusimano, Michael D., Bernstein, Mark, Batada, Nizar, Angers, Stephane, Dirks, Peter B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499328/
https://www.ncbi.nlm.nih.gov/pubmed/30842215
http://dx.doi.org/10.1101/gad.321968.118

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