STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism

Mitophagy is the selective autophagic targeting and removal of dysfunctional mitochondria. While PINK1/Parkin-dependent mitophagy is well-characterized, PINK1/Parkin-independent route is poorly understood. Using structure illumination microscopy (SR-SIM), we demonstrate that the SNARE protein Syntax...

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Detalles Bibliográficos
Autores principales: Xian, Hongxu, Yang, Qiaoyun, Xiao, Lin, Shen, Han-Ming, Liou, Yih-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499814/
https://www.ncbi.nlm.nih.gov/pubmed/31053718
http://dx.doi.org/10.1038/s41467-019-10096-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499814/
https://www.ncbi.nlm.nih.gov/pubmed/31053718
http://dx.doi.org/10.1038/s41467-019-10096-1

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