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NLRP3 inflammasome activation in platelets in response to sepsis

Sepsis is a complex syndrome characterized by organ dysfunction and a dysregulated immune host response to infection. There is currently no effective treatment for sepsis, but platelets have been proposed as a potential therapeutic target for the treatment of sepsis. We hypothesized that the NLRP3 i...

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Detalles Bibliográficos
Autores principales: Cornelius, Denise C., Baik, Cedar H., Travis, Olivia K., White, Dakota L., Young, Cassandra M., Austin Pierce, W., Shields, Corbin A., Poudel, Bibek, Williams, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499866/
https://www.ncbi.nlm.nih.gov/pubmed/31054188
http://dx.doi.org/10.14814/phy2.14073