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Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia

Rabbit antithymocyte globulin (rATG) is known to yield false-positive Histoplasma antigenemia. The fourth generation MiraVista Histoplasma antigen assay was modified to block this effect (MiraVista Diagnostics, Indianapolis, Indiana). We report a case of rATG-induced false-positive Blastomyces and H...

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Autores principales: Kaur, Amrit, Eberlein, Michael, Klesney-Tait, Julia, Durkin, Michelle M, Wheat, L Joseph, Gajurel, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499897/
https://www.ncbi.nlm.nih.gov/pubmed/31065562
http://dx.doi.org/10.1093/ofid/ofz165
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author Kaur, Amrit
Eberlein, Michael
Klesney-Tait, Julia
Durkin, Michelle M
Wheat, L Joseph
Gajurel, Kiran
author_facet Kaur, Amrit
Eberlein, Michael
Klesney-Tait, Julia
Durkin, Michelle M
Wheat, L Joseph
Gajurel, Kiran
author_sort Kaur, Amrit
collection PubMed
description Rabbit antithymocyte globulin (rATG) is known to yield false-positive Histoplasma antigenemia. The fourth generation MiraVista Histoplasma antigen assay was modified to block this effect (MiraVista Diagnostics, Indianapolis, Indiana). We report a case of rATG-induced false-positive Blastomyces and Histoplasma antigenemia in a lung transplant recipient despite modifications of these antigen assays.
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spelling pubmed-64998972019-05-07 Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia Kaur, Amrit Eberlein, Michael Klesney-Tait, Julia Durkin, Michelle M Wheat, L Joseph Gajurel, Kiran Open Forum Infect Dis Brief Report Rabbit antithymocyte globulin (rATG) is known to yield false-positive Histoplasma antigenemia. The fourth generation MiraVista Histoplasma antigen assay was modified to block this effect (MiraVista Diagnostics, Indianapolis, Indiana). We report a case of rATG-induced false-positive Blastomyces and Histoplasma antigenemia in a lung transplant recipient despite modifications of these antigen assays. Oxford University Press 2019-03-28 /pmc/articles/PMC6499897/ /pubmed/31065562 http://dx.doi.org/10.1093/ofid/ofz165 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Kaur, Amrit
Eberlein, Michael
Klesney-Tait, Julia
Durkin, Michelle M
Wheat, L Joseph
Gajurel, Kiran
Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title_full Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title_fullStr Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title_full_unstemmed Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title_short Rabbit Antithymocyte Globulin Causes Blastomyces and Histoplasma Antigenemia
title_sort rabbit antithymocyte globulin causes blastomyces and histoplasma antigenemia
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499897/
https://www.ncbi.nlm.nih.gov/pubmed/31065562
http://dx.doi.org/10.1093/ofid/ofz165
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