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miR-21-5p protects IL-1β-induced human chondrocytes from degradation

OBJECTIVE: Osteoarthritis (OA) is a prevalent degenerative disease caused by various factors. MicroRNAs are important regulators in OA. MiR-21-5p expression is decreased in OA cartilage, but the effects of modulating miR-21-5p on cartilage regeneration are unknown. Therefore, our aim was to investig...

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Detalles Bibliográficos
Autores principales: Zhu, Hai, Yan, Xin, Zhang, Meng, Ji, Feng, Wang, Shouguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499971/
https://www.ncbi.nlm.nih.gov/pubmed/31053150
http://dx.doi.org/10.1186/s13018-019-1160-7