LncRNA SNHG1 contributes to sorafenib resistance by activating the Akt pathway and is positively regulated by miR-21 in hepatocellular carcinoma cells

BACKGROUND: Acquired resistance to sorafenib greatly limits its therapeutic efficiency in the treatment of hepatocellular carcinoma (HCC). Increasing evidence indicates that long noncoding RNAs (lncRNAs) play important roles in the resistance to anti-cancer drugs. The present study aims to explore t...

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Detalles Bibliográficos
Autores principales: Li, Weidong, Dong, Xuesong, He, Changjun, Tan, Gang, Li, Ziyi, Zhai, Bo, Feng, Jing, Jiang, Xian, Liu, Chang, Jiang, Hongchi, Sun, Xueying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6499991/
https://www.ncbi.nlm.nih.gov/pubmed/31053148
http://dx.doi.org/10.1186/s13046-019-1177-0

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