Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

Intrinsically disordered proteins (IDPs) and their conformational transitions play an important role in neurotransmitter release at the neuronal synapse. Here, the SNARE proteins are essential by forming the SNARE complex that drives vesicular membrane fusion. While it is widely accepted that the SN...

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Detalles Bibliográficos
Autores principales: Lakomek, Nils-Alexander, Yavuz, Halenur, Jahn, Reinhard, Pérez-Lara, Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500178/
https://www.ncbi.nlm.nih.gov/pubmed/30975750
http://dx.doi.org/10.1073/pnas.1813194116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500178/
https://www.ncbi.nlm.nih.gov/pubmed/30975750
http://dx.doi.org/10.1073/pnas.1813194116

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