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Protocol for the Gut Bugs Trial: a randomised double-blind placebo-controlled trial of gut microbiome transfer for the treatment of obesity in adolescents

INTRODUCTION: Animal studies showed that germ-free mice inoculated with normal mouse gut bacteria developed obesity, insulin resistance and higher triglyceride levels, despite similar food intake. In humans, an association has been found between obesity and gut microbiome dysbiosis. However, gut mic...

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Detalles Bibliográficos
Autores principales: Leong, Karen S W, Jayasinghe, Thilini N, Derraik, José G B, Albert, Benjamin B, Chiavaroli, Valentina, Svirskis, Darren M, Beck, Kathryn L, Conlon, Cathryn A, Jiang, Yannan, Schierding, William, Vatanen, Tommi, Holland, David J, O’Sullivan, Justin M, Cutfield, Wayne S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500264/
https://www.ncbi.nlm.nih.gov/pubmed/31005929
http://dx.doi.org/10.1136/bmjopen-2018-026174