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Protocol for the Gut Bugs Trial: a randomised double-blind placebo-controlled trial of gut microbiome transfer for the treatment of obesity in adolescents
INTRODUCTION: Animal studies showed that germ-free mice inoculated with normal mouse gut bacteria developed obesity, insulin resistance and higher triglyceride levels, despite similar food intake. In humans, an association has been found between obesity and gut microbiome dysbiosis. However, gut mic...
Autores principales: | Leong, Karen S W, Jayasinghe, Thilini N, Derraik, José G B, Albert, Benjamin B, Chiavaroli, Valentina, Svirskis, Darren M, Beck, Kathryn L, Conlon, Cathryn A, Jiang, Yannan, Schierding, William, Vatanen, Tommi, Holland, David J, O’Sullivan, Justin M, Cutfield, Wayne S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500264/ https://www.ncbi.nlm.nih.gov/pubmed/31005929 http://dx.doi.org/10.1136/bmjopen-2018-026174 |
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