AMBIsome Therapy Induction OptimisatioN (AMBITION): High dose AmBisome for cryptococcal meningitis induction therapy in sub-Saharan Africa: economic evaluation protocol for a randomised controlled trial-based equivalence study

INTRODUCTION: Cryptococcal meningitis is responsible for around 15% of all HIV-related deaths globally. Conventional treatment courses with amphotericin B require prolonged hospitalisation and are associated with multiple toxicities and poor outcomes. A phase II study has shown that a single high do...

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Autores principales: Ponatshego, Ponego Lloyd, Lawrence, David Stephen, Youssouf, Nabila, Molloy, Sile F, Alufandika, Melanie, Bango, Funeka, Boulware, David R, Chawinga, Chimwemwe, Dziwani, Eltas, Gondwe, Ebbie, Hlupeni, Admire, Hosseinipour, Mina C, Kanyama, Cecilia, Meya, David B, Mosepele, Mosepele, Muthoga, Charles, Muzoora, Conrad K, Mwandumba, Henry, Ndhlovu, Chiratidzo E, Rajasingham, Radha, Sayed, Sumaya, Shamu, Shepherd, Tsholo, Katlego, Tugume, Lillian, Williams, Darlisha, Maheswaran, Hendramoorthy, Shiri, Tinevimbo, Boyer-Chammard, Timothée, Loyse, Angela, Chen, Tao, Wang, Duolao, Lortholary, Olivier, Lalloo, David G, Meintjes, Graeme, Jaffar, Shabbar, Harrison, Thomas S, Jarvis, Joseph N, Niessen, Louis Wilhelmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Infectious Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500286/
https://www.ncbi.nlm.nih.gov/pubmed/30940760
http://dx.doi.org/10.1136/bmjopen-2018-026288

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