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Role of Gut Microbiota in the Pharmacological Effects of Natural Products
Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolite...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500626/ https://www.ncbi.nlm.nih.gov/pubmed/31118952 http://dx.doi.org/10.1155/2019/2682748 |
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author | Pan, Chuyue Guo, Qinglong Lu, Na |
author_facet | Pan, Chuyue Guo, Qinglong Lu, Na |
author_sort | Pan, Chuyue |
collection | PubMed |
description | Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolites, intestinal tight junction structure, and mucosal immunology. These changes will eventually result in the exertion of the pharmacological effects by treatment with these natural products. In this review, we will discuss how gut microbiota is influenced by commonly used natural products. Furthermore, our findings are expected to provide novel insight into how these untargeted natural products function via gut microbiota. |
format | Online Article Text |
id | pubmed-6500626 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-65006262019-05-22 Role of Gut Microbiota in the Pharmacological Effects of Natural Products Pan, Chuyue Guo, Qinglong Lu, Na Evid Based Complement Alternat Med Review Article Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolites, intestinal tight junction structure, and mucosal immunology. These changes will eventually result in the exertion of the pharmacological effects by treatment with these natural products. In this review, we will discuss how gut microbiota is influenced by commonly used natural products. Furthermore, our findings are expected to provide novel insight into how these untargeted natural products function via gut microbiota. Hindawi 2019-04-15 /pmc/articles/PMC6500626/ /pubmed/31118952 http://dx.doi.org/10.1155/2019/2682748 Text en Copyright © 2019 Chuyue Pan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Pan, Chuyue Guo, Qinglong Lu, Na Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title | Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title_full | Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title_fullStr | Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title_full_unstemmed | Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title_short | Role of Gut Microbiota in the Pharmacological Effects of Natural Products |
title_sort | role of gut microbiota in the pharmacological effects of natural products |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500626/ https://www.ncbi.nlm.nih.gov/pubmed/31118952 http://dx.doi.org/10.1155/2019/2682748 |
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