Cargando…

Role of Gut Microbiota in the Pharmacological Effects of Natural Products

Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolite...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Chuyue, Guo, Qinglong, Lu, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500626/
https://www.ncbi.nlm.nih.gov/pubmed/31118952
http://dx.doi.org/10.1155/2019/2682748
_version_ 1783415983432531968
author Pan, Chuyue
Guo, Qinglong
Lu, Na
author_facet Pan, Chuyue
Guo, Qinglong
Lu, Na
author_sort Pan, Chuyue
collection PubMed
description Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolites, intestinal tight junction structure, and mucosal immunology. These changes will eventually result in the exertion of the pharmacological effects by treatment with these natural products. In this review, we will discuss how gut microbiota is influenced by commonly used natural products. Furthermore, our findings are expected to provide novel insight into how these untargeted natural products function via gut microbiota.
format Online
Article
Text
id pubmed-6500626
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-65006262019-05-22 Role of Gut Microbiota in the Pharmacological Effects of Natural Products Pan, Chuyue Guo, Qinglong Lu, Na Evid Based Complement Alternat Med Review Article Increasing evidence has demonstrated that natural products derived from traditional Chinese medicine, such as ginseng, berberine, and curcumin, possess a wide variety of biological activities on gut microbiota, which may cause changes in the composition of intestinal microbiota, microbial metabolites, intestinal tight junction structure, and mucosal immunology. These changes will eventually result in the exertion of the pharmacological effects by treatment with these natural products. In this review, we will discuss how gut microbiota is influenced by commonly used natural products. Furthermore, our findings are expected to provide novel insight into how these untargeted natural products function via gut microbiota. Hindawi 2019-04-15 /pmc/articles/PMC6500626/ /pubmed/31118952 http://dx.doi.org/10.1155/2019/2682748 Text en Copyright © 2019 Chuyue Pan et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pan, Chuyue
Guo, Qinglong
Lu, Na
Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title_full Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title_fullStr Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title_full_unstemmed Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title_short Role of Gut Microbiota in the Pharmacological Effects of Natural Products
title_sort role of gut microbiota in the pharmacological effects of natural products
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500626/
https://www.ncbi.nlm.nih.gov/pubmed/31118952
http://dx.doi.org/10.1155/2019/2682748
work_keys_str_mv AT panchuyue roleofgutmicrobiotainthepharmacologicaleffectsofnaturalproducts
AT guoqinglong roleofgutmicrobiotainthepharmacologicaleffectsofnaturalproducts
AT luna roleofgutmicrobiotainthepharmacologicaleffectsofnaturalproducts