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CD44 aptamer mediated cargo delivery to lysosomes of retinal pigment epithelial cells to prevent age-related macular degeneration

Age related macular degeneration (AMD) is a progressive, neurodegenerative disorder that leads to the severe loss of central vision in elderlies. The health of retinal pigment epithelial (RPE) cells is critical for the onset of AMD. Chronic oxidative stress along with loss of lysosomal activity is a...

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Detalles Bibliográficos
Autores principales:	Chandola, Chetan, Casteleijn, Marco G., Chandola, Urvashi M., Gopalan, Lakshmi Narayanan, Urtti, Arto, Neerathilingam, Muniasamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500919/ https://www.ncbi.nlm.nih.gov/pubmed/31080896 http://dx.doi.org/10.1016/j.bbrep.2019.100642

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