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DPPA2 and DPPA4 are necessary to establish a 2C‐like state in mouse embryonic stem cells
After fertilization of the transcriptionally silent oocyte, expression from both parental chromosomes is launched through zygotic genome activation (ZGA), occurring in the mouse at the 2‐cell (2C) stage. Among the first elements to be transcribed are the Dux gene, the product of which induces a wide...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500978/ https://www.ncbi.nlm.nih.gov/pubmed/30948459 http://dx.doi.org/10.15252/embr.201847382 |