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DPPA2 and DPPA4 are necessary to establish a 2C‐like state in mouse embryonic stem cells

After fertilization of the transcriptionally silent oocyte, expression from both parental chromosomes is launched through zygotic genome activation (ZGA), occurring in the mouse at the 2‐cell (2C) stage. Among the first elements to be transcribed are the Dux gene, the product of which induces a wide...

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Detalles Bibliográficos
Autores principales:	De Iaco, Alberto, Coudray, Alexandre, Duc, Julien, Trono, Didier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Scientific Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500978/ https://www.ncbi.nlm.nih.gov/pubmed/30948459 http://dx.doi.org/10.15252/embr.201847382

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