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KMT1 family methyltransferases regulate heterochromatin–nuclear periphery tethering via histone and non‐histone protein methylation

Euchromatic histone methyltransferases (EHMTs), members of the KMT1 family, methylate histone and non‐histone proteins. Here, we uncover a novel role for EHMTs in regulating heterochromatin anchorage to the nuclear periphery (NP) via non‐histone methylation. We show that EHMTs methylate and stabiliz...

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Detalles Bibliográficos
Autores principales: Rao, Radhika Arasala, Ketkar, Alhad Ashok, Kedia, Neelam, Krishnamoorthy, Vignesh K, Lakshmanan, Vairavan, Kumar, Pankaj, Mohanty, Abhishek, Kumar, Shilpa Dilip, Raja, Sufi O, Gulyani, Akash, Chaturvedi, Chandra Prakash, Brand, Marjorie, Palakodeti, Dasaradhi, Rampalli, Shravanti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501005/
https://www.ncbi.nlm.nih.gov/pubmed/30858340
http://dx.doi.org/10.15252/embr.201643260