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Structural basis of HEAT‐kleisin interactions in the human condensin I subcomplex

Condensin I is a multi‐protein complex that plays an essential role in mitotic chromosome assembly and segregation in eukaryotes. It is composed of five subunits: two SMC (SMC2 and SMC4), a kleisin (CAP‐H), and two HEAT‐repeat (CAP‐D2 and CAP‐G) subunits. Although balancing acts of the two HEAT‐repe...

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Detalles Bibliográficos
Autores principales: Hara, Kodai, Kinoshita, Kazuhisa, Migita, Tomoko, Murakami, Kei, Shimizu, Kenichiro, Takeuchi, Kozo, Hirano, Tatsuya, Hashimoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501013/
https://www.ncbi.nlm.nih.gov/pubmed/30858338
http://dx.doi.org/10.15252/embr.201847183

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