Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say

Aim: This study aimed to evaluate larvicidal activity of Hypoestes forskaolii R. Br root extract against 3rd instar Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Methods: A protocol developed by the World Health Organization was adopted, with minor modification using chloroform and m...

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Autores principales: Sillo, Albert J, Makirita, Winisia E, Swai, Hulda, Chacha, Musa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501056/
https://www.ncbi.nlm.nih.gov/pubmed/31118834
http://dx.doi.org/10.2147/JEP.S187837
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author Sillo, Albert J
Makirita, Winisia E
Swai, Hulda
Chacha, Musa
author_facet Sillo, Albert J
Makirita, Winisia E
Swai, Hulda
Chacha, Musa
author_sort Sillo, Albert J
collection PubMed
description Aim: This study aimed to evaluate larvicidal activity of Hypoestes forskaolii R. Br root extract against 3rd instar Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Methods: A protocol developed by the World Health Organization was adopted, with minor modification using chloroform and methanol extracts with concentrations ranging from 25–750 µg/mL. Results: The H. forskaolii chloroform extract exhibited very high larvicidal activity after 72 hours of exposure, with LC(50) 2.0322, 3.8989, 6.0004 μg/mL against A. gambiae, A. aegypti, and C. quinquefasciatus, respectively. Conclusion: The larvicidal activity of H. forskaolii is reported for the first time in this paper. The effectiveness of H. forskaolii chloroform extract warrants further research to develop botanical mosquito repellants from this source.
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spelling pubmed-65010562019-05-22 Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say Sillo, Albert J Makirita, Winisia E Swai, Hulda Chacha, Musa J Exp Pharmacol Original Research Aim: This study aimed to evaluate larvicidal activity of Hypoestes forskaolii R. Br root extract against 3rd instar Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. Methods: A protocol developed by the World Health Organization was adopted, with minor modification using chloroform and methanol extracts with concentrations ranging from 25–750 µg/mL. Results: The H. forskaolii chloroform extract exhibited very high larvicidal activity after 72 hours of exposure, with LC(50) 2.0322, 3.8989, 6.0004 μg/mL against A. gambiae, A. aegypti, and C. quinquefasciatus, respectively. Conclusion: The larvicidal activity of H. forskaolii is reported for the first time in this paper. The effectiveness of H. forskaolii chloroform extract warrants further research to develop botanical mosquito repellants from this source. Dove 2019-04-26 /pmc/articles/PMC6501056/ /pubmed/31118834 http://dx.doi.org/10.2147/JEP.S187837 Text en © 2019 Sillo et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Sillo, Albert J
Makirita, Winisia E
Swai, Hulda
Chacha, Musa
Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title_full Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title_fullStr Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title_full_unstemmed Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title_short Larvicidal activity of Hypoestes forskaolii (Vahl) R. Br root extracts against Anopheles gambiae Giless.s, Aedes aegypti L, and Culex quinquefasciatus Say
title_sort larvicidal activity of hypoestes forskaolii (vahl) r. br root extracts against anopheles gambiae giless.s, aedes aegypti l, and culex quinquefasciatus say
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501056/
https://www.ncbi.nlm.nih.gov/pubmed/31118834
http://dx.doi.org/10.2147/JEP.S187837
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