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CD33 (Siglec-3) Inhibitory Function: Role in the NKG2D/DAP10 Activating Pathway
CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism of the innate immune system; nevertheless, its role as an inhibitory recep...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501159/ https://www.ncbi.nlm.nih.gov/pubmed/31143782 http://dx.doi.org/10.1155/2019/6032141 |