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A case report of therapeutically challenging chronic actinic dermatitis
Chronic actinic dermatitis is a difficult to treat photodermatitis. Treatment is not standardized and involves topical corticosteroids and immunomodulators, and systemic immunosuppressive agents. We present a case with partial response to dupilumab, a monoclonal antibody approved for atopic dermatit...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501497/ https://www.ncbi.nlm.nih.gov/pubmed/31105944 http://dx.doi.org/10.1177/2050313X19845235 |
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author | Verma, Luvneet Pratt, Melanie |
author_facet | Verma, Luvneet Pratt, Melanie |
author_sort | Verma, Luvneet |
collection | PubMed |
description | Chronic actinic dermatitis is a difficult to treat photodermatitis. Treatment is not standardized and involves topical corticosteroids and immunomodulators, and systemic immunosuppressive agents. We present a case with partial response to dupilumab, a monoclonal antibody approved for atopic dermatitis. In recalcitrant cases, systemic agents such as methotrexate, azathioprine, mycophenolate mofetil, and thalidomide, extracorpeal electrophoresis, and low-dose psoralen and ultraviolet A can also be considered. |
format | Online Article Text |
id | pubmed-6501497 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-65014972019-05-17 A case report of therapeutically challenging chronic actinic dermatitis Verma, Luvneet Pratt, Melanie SAGE Open Med Case Rep JCMS Case Report Chronic actinic dermatitis is a difficult to treat photodermatitis. Treatment is not standardized and involves topical corticosteroids and immunomodulators, and systemic immunosuppressive agents. We present a case with partial response to dupilumab, a monoclonal antibody approved for atopic dermatitis. In recalcitrant cases, systemic agents such as methotrexate, azathioprine, mycophenolate mofetil, and thalidomide, extracorpeal electrophoresis, and low-dose psoralen and ultraviolet A can also be considered. SAGE Publications 2019-05-02 /pmc/articles/PMC6501497/ /pubmed/31105944 http://dx.doi.org/10.1177/2050313X19845235 Text en © The Author(s) 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | JCMS Case Report Verma, Luvneet Pratt, Melanie A case report of therapeutically challenging chronic actinic dermatitis |
title | A case report of therapeutically challenging chronic actinic dermatitis |
title_full | A case report of therapeutically challenging chronic actinic dermatitis |
title_fullStr | A case report of therapeutically challenging chronic actinic dermatitis |
title_full_unstemmed | A case report of therapeutically challenging chronic actinic dermatitis |
title_short | A case report of therapeutically challenging chronic actinic dermatitis |
title_sort | case report of therapeutically challenging chronic actinic dermatitis |
topic | JCMS Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501497/ https://www.ncbi.nlm.nih.gov/pubmed/31105944 http://dx.doi.org/10.1177/2050313X19845235 |
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